Professor Christian Tientcha Happi is a Professor of Molecular Biology and Genomics in the Department of Biological Sciences, and the Director African Center of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer’s University. He holds a BSc in Biochemistry, MSc and PhD in Molecular Parasitology from the University of Ibadan in 1993, 1995 and 2000 respectively. He did his post-doctoral research in Molecular Biology and Genomics at the Harvard University, School of Public Health, Boston, MA, USA (2000-2003). He is currently the Director, Directorate of Research Innovations and Partnerships (DRIPs), Redeemer’s University.
Current Research Interest
My research focus is on Human Genomics, Molecular Biology and Genomics of Infectious Diseases, especially Malaria, Viral Haemorrhagic Fevers (Lassa fever, Ebola Virus Disease, and others), and HIV.
My current research activities consist of using innovative approaches that combines patient care, fieldwork, laboratory, molecular biology and genomics methods for discoveries that have shifted the paradigm in clinical research and applications in parasites and viral diagnosis, parasites biology and genomics, Pharmacogenomics, and human genomics. In addition, I am passionate about building research capacity and human resource through training and mentoring activities.
Through my research, we have been able to identify molecular markers of antimalarial drug resistance in Plasmodium falciparum, the agent of malaria. We recently discovered new viruses (EKV-1 and EKV-2, and developed new rapid diagnoses for Ebola virus disease (EVD), and Lassa fever virus.
My laboratory confirmed the first case of Ebola Virus Disease in Nigeria in the 2014 Ebola outbreak, and work with Nigerian Health Officials for the successful containment of the Ebola outbreak in Nigeria.
Research work in my laboratory contributed significantly to the establishment of the global reference for human genetic variation. Our research work has also resulted in the identification of new genes associated with human resistance to infection to Lassa fever virus